sure is a delicate balance. I was interested in miR-494 (and wondered if I should have more milk), and have relied upon chatGPT to tell me more. I found it seemed to say balance was needed. "In moderation, miR-494 supports cellular repair, immune balance, and metabolic function. Too much miR-494 may impair mitochondrial function, increase inflammation, and contribute to tissue aging." Seems there is so much more to learn about when and who might benefit from stimulating or reducing this!
miRNAs are such a fascinating topic. They can influence gene expression for hundreds of different genes, which is why using them in large amounts, such as in a drug or a shot, is likely to have too many off-target effects (such as impaired mitochondrial function). There's a bunch of research going on with miRNAs for cancer.
Hi, this is very interesting. Another possible pathway to understand and maybe slow down aging. Would be interesting if we at some point could understand whether there are natural ways of decreasing EDA2R. I suspect the usual suspects such as exercise, sleep, diet, stres, etc. But perhaps there are certain plants that are beneficial..
sure is a delicate balance. I was interested in miR-494 (and wondered if I should have more milk), and have relied upon chatGPT to tell me more. I found it seemed to say balance was needed. "In moderation, miR-494 supports cellular repair, immune balance, and metabolic function. Too much miR-494 may impair mitochondrial function, increase inflammation, and contribute to tissue aging." Seems there is so much more to learn about when and who might benefit from stimulating or reducing this!
miRNAs are such a fascinating topic. They can influence gene expression for hundreds of different genes, which is why using them in large amounts, such as in a drug or a shot, is likely to have too many off-target effects (such as impaired mitochondrial function). There's a bunch of research going on with miRNAs for cancer.
Here's my article with more background on miRNAs, if you want to read more: https://www.geneticlifehacks.com/mirna-what-it-is-and-how-it-works/
The more we decode EDA2R , the more we see: aging is not random, but orchestrated.
Orchestrated by genetic expression, cellular signals, and the slow breakdown of our protective barriers.
Hi, this is very interesting. Another possible pathway to understand and maybe slow down aging. Would be interesting if we at some point could understand whether there are natural ways of decreasing EDA2R. I suspect the usual suspects such as exercise, sleep, diet, stres, etc. But perhaps there are certain plants that are beneficial..